Urinary Kidney Injury Molecule-1 and the Risk of Cardiovascular Mortality in Elderly Men
نویسندگان
چکیده
منابع مشابه
Urinary kidney injury molecule-1 and the risk of cardiovascular mortality in elderly men.
BACKGROUND AND OBJECTIVES Kidney injury molecule-1 (KIM-1) has been suggested as a clinically relevant highly specific biomarker of acute kidney tubular damage. However, community-based data on the association between urinary levels of KIM-1 and the risk for cardiovascular mortality are lacking. This study aimed to investigate the association between urinary KIM-1 and cardiovascular mortality. ...
متن کاملAssociations between urinary kidney injury biomarkers and cardiovascular mortality risk in elderly men with diabetes
AIM Three urinary biomarkers, kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), and cystatin C, have been suggested as clinically relevant highly specific biomarkers of acute kidney tubular damage. Yet, the utility of these biomarkers in the prognostication of diabetic nephropathy has been less studied. Therefore, we aimed to investigate the longitudinal assoc...
متن کاملUrinary kidney injury molecule 1 and incidence of heart failure in elderly men.
AIMS There is growing recognition of the clinical importance of cardiorenal syndrome-the bidirectional interplay between kidney and cardiac dysfunction. Yet, the role of kidney tubular damage in the development of heart failure is less studied. The objective of this study was to investigate whether urinary kidney injury molecule (KIM)-1, a specific marker of tubular damage, predisposes to an in...
متن کاملDiagnostic Value of Urinary Kidney Injury Molecule 1 for Acute Kidney Injury: A Meta-Analysis
BACKGROUND Urinary Kidney Injury Molecule 1 (KIM-1) is a proximal tubular injury biomarker for early detection of acute kidney injury (AKI), with variable performance characteristics depending on clinical and population settings. METHODS Meta-analysis was performed to assess the diagnostic value of urinary KIM-1 in AKI. Relevant studies were searched from MEDLINE, EMBASE, Pubmed, Elsevier Sci...
متن کاملUrinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury.
Sensitive and specific biomarkers are needed to detect early kidney injury. The objective of the present work was to develop a sensitive quantitative urinary test to identify renal injury in the rodent to facilitate early assessment of pathophysiological influences and drug toxicity. Two mouse monoclonal antibodies were made against the purified ectodomain of kidney injury molecule-1 (Kim-1), a...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2014
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.11901113